Alzheimer's Disease

bio-intelligence/neuroscience/alzheimers-disease.md Current Note ID: The unique ID of this note.
#neuroscience

Pathology

  1. Amyloid-beta deposition in grey matter for Alzheimer’s disease. Accumulation of amyloid-beta then leads to oligomers which finally form plaques. It can alter intracellular Ca2+ levels. 1
  2. Amyloid-beta can transmit between human 2

Network Dysfunction

  1. Hypersynchrony and altered oscillatory rhythmic activity 3

  1. Intracellular amyloid-β in Alzheimer’s disease (Figure 3 is a nice illustration of the process), Poster: Amyloid-β and tau in Alzheimer’s disease ↩︎

  2. Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy ↩︎

  3. Network abnormalities and interneuron dysfunction in Alzheimer disease ↩︎

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Lei Ma (2020). 'Alzheimer's Disease', Intelligence, 05 April. Available at: https://intelligence.leima.is/bio-intelligence/neuroscience/alzheimers-disease/.